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. 1976 Feb;37(2):95-102.
doi: 10.1080/0002889768507418.

Toxicity and metabolism of methyl n-butyl ketone

M S Abdel-Rahman, L B Hetland, D Couri

Toxicity and metabolism of methyl n-butyl ketone

M S Abdel-Rahman et al. Am Ind Hyg Assoc J. 1976 Feb.

Abstract

MEK (2-butanone) when combined with MBK (2-hexanone) markedly enhanced MBK neurotoxicity. MBK in rat plasma after exposure to MBK/MEK increased with time. Metabolites of MBK identified in blood and urine of rats and guinea pigs were 2-hexanol and 2,5-hexanedione.

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