Toxicity and metabolism of methyl n-butyl ketone
- PMID: 175651
- DOI: 10.1080/0002889768507418
Toxicity and metabolism of methyl n-butyl ketone
Abstract
MEK (2-butanone) when combined with MBK (2-hexanone) markedly enhanced MBK neurotoxicity. MBK in rat plasma after exposure to MBK/MEK increased with time. Metabolites of MBK identified in blood and urine of rats and guinea pigs were 2-hexanol and 2,5-hexanedione.
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