Granulocytic sarcoma: an unusual cause of spinal cord compression

Abstract

A 76-year old woman presented with a large inguino-crural mass, multiple abdominal lymphoadenopathies, and neurological signs of spinal cord compression, first diagnosed as large-cell non-Hodgkin lymphoma. At subsequent clinical workup, a diagnosis of granulocytic sarcoma with meningeal involvement was made. Unfortunately, despite receiving intensive care, shortly after induction chemotherapy, the patient died of acute pneumonia followed by acute respiratory distress syndrome. The case is discussed in the framework of the existing literature and to derive clinical practice recommendations for this rare condition.