The tissue factor-factor VIIa complex: procoagulant activity, regulation, and multitasking
- PMID: 17567444
- DOI: 10.1111/j.1538-7836.2007.02435.x
The tissue factor-factor VIIa complex: procoagulant activity, regulation, and multitasking
Abstract
Greater understanding of the cellular interactions associated with tissue factor (TF), activated factor (F) VII and TF-FVIIa complexes is likely to provide considerable clinical benefit. This article reviews current knowledge on the function and regulation of TF and its role in a range of biological processes, including hemostasis, thrombosis and inflammation.
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