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Comparative Study
. 2007 Aug;45(8):2737-9.
doi: 10.1128/JCM.00686-07. Epub 2007 Jun 13.

Detection of Clostridium difficile toxin: comparison of enzyme immunoassay results with results obtained by cytotoxicity assay

Daniel M Musher  1 , Atisha Manhas, Pranav Jain, Franziska Nuila, Amna Waqar, Nancy Logan, Bernard Marino, Edward A Graviss
Affiliations
Comparative Study

Detection of Clostridium difficile toxin: comparison of enzyme immunoassay results with results obtained by cytotoxicity assay

Daniel M Musher et al. J Clin Microbiol. 2007 Aug.

Abstract

Several kinds of laboratory techniques are available to detect Clostridium difficile toxin in fecal samples. Because questions have been raised about the reliability of immunoassays compared to the accepted standard, cytotoxicity assay, we studied three enzyme immunoassays (EIAs) and one rapid EIA, which demonstrated relatively good sensitivities and specificities compared to cytotoxicity assay.

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