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Review
. 2007 Mar;216(1):1-16.
doi: 10.1007/s00232-007-9019-y. Epub 2007 Jun 14.

The lens circulation

Richard T Mathias  1 , Joerg Kistler, Paul Donaldson
Affiliations
Review

The lens circulation

Richard T Mathias et al. J Membr Biol. 2007 Mar.

Abstract

The lens is the largest organ in the body that lacks a vasculature. The reason is simple: blood vessels scatter and absorb light while the physiological role of the lens is to be transparent so it can assist the cornea in focusing light on the retina. We hypothesize this lack of blood supply has led the lens to evolve an internal circulation of ions that is coupled to fluid movement, thus creating an internal micro-circulatory system, which makes up for the lack of vasculature. This review covers the membrane transport systems that are believed to generate and direct this internal circulatory system.

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References

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