doi: 10.1126/science.199.4324.77.
Thyroid gangliosides with high affinity for thyrotropin: potential role in thyroid regulation
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- PMID: 17569488
- DOI: 10.1126/science.199.4324.77
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Thyroid gangliosides with high affinity for thyrotropin: potential role in thyroid regulation
Science.
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Abstract
Thyroid cell membranes contain a multiplicity of gangliosides, some of which inhibit thyrotropin binding to thyroid membranes. The most potent inhibitor is a ganglioside which is present in only trace amounts and appears to have a novel structure. Thyroid gangliosides may play a role in relaying the hormonal message to the thyroid cell.
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