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Case Reports
. 2007 Jun;82(6):377-80.
doi: 10.4321/s0365-66912007000600012.

[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy]

[Article in Spanish]
N Barnils  1 , E Mesa, S Muñoz, A Ferrer-Artola, J Arruga
Affiliations
Case Reports

[Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy]

[Article in Spanish]
N Barnils et al. Arch Soc Esp Oftalmol. 2007 Jun.

Abstract

Objective: To ascertain the efficacy of idebenone and multivitamin treatment in Leber's hereditary optic neuropathy (LHON).

Method: Two patients diagnosed of unilateral LHON were treated with megadoses of idebenone, vitamin C and riboflavin for one year. They were examined clinically before, during and after treatment.

Results: No improvement of visual function was observed. Despite the idebenone treatment, in both cases the second eye became involved.

Conclusions: Despite previous reports of visual recovery with idebenone in patients with LHON, our experience shows that an effective treatment for Leber's disease remains to be found.

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