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Review
. 2007 Nov:40 Suppl:S52-60.
doi: 10.1002/eat.20398.

Genetic epidemiology, endophenotypes, and eating disorder classification

Affiliations
Review

Genetic epidemiology, endophenotypes, and eating disorder classification

Cynthia M Bulik et al. Int J Eat Disord. 2007 Nov.

Abstract

Objective: To explore how genetic epidemiology has informed the identification of endophenotypes and how endophenotypes may inform future classification of eating disorders.

Method: Literature review and synthesis.

Results: Although a number of endo- and subphenotypes have been suggested for eating disorders, few reach the rigorous definitions developed for candidate endophenotypes.

Conclusion: Further study of endophenotypes and subphenotypes for eating disorders may assist with developing a more homogenous classification system that more closely reflects underlying biological mechanisms, and provides a clearer focus for the development of coherent models and treatments.

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