Genetic epidemiology, endophenotypes, and eating disorder classification
- PMID: 17573683
- DOI: 10.1002/eat.20398
Genetic epidemiology, endophenotypes, and eating disorder classification
Abstract
Objective: To explore how genetic epidemiology has informed the identification of endophenotypes and how endophenotypes may inform future classification of eating disorders.
Method: Literature review and synthesis.
Results: Although a number of endo- and subphenotypes have been suggested for eating disorders, few reach the rigorous definitions developed for candidate endophenotypes.
Conclusion: Further study of endophenotypes and subphenotypes for eating disorders may assist with developing a more homogenous classification system that more closely reflects underlying biological mechanisms, and provides a clearer focus for the development of coherent models and treatments.
(c) 2007 by Wiley Periodicals, Inc.
Comment in
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Genetic epidemiology of eating disorders and co-occurring conditions: the role of endophenotypes.Int J Eat Disord. 2007 Nov;40 Suppl:S76-8. doi: 10.1002/eat.20457. Int J Eat Disord. 2007. PMID: 17868129 No abstract available.
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