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Randomized Controlled Trial
. 2007 Dec;11(4):425-9.
doi: 10.1007/s00784-007-0129-9. Epub 2007 Jun 16.

Effect of chewing gums containing xylitol or probiotic bacteria on salivary mutans streptococci and lactobacilli

Affiliations
Randomized Controlled Trial

Effect of chewing gums containing xylitol or probiotic bacteria on salivary mutans streptococci and lactobacilli

E Caglar et al. Clin Oral Investig. 2007 Dec.

Abstract

The aim was to evaluate the effect of xylitol and probiotic chewing gums on salivary mutans streptococci (MS) and lactobacilli (LB). The material consisted of 80 healthy young adults (21-24 years) who volunteered after informed consent. They were assigned by random into one of four parallel study groups: A, probiotic gum group; B, xylitol gum group; C, probiotic + xylitol gum group; and D, placebo gum group. The gums were taken three times daily after meals, and the intervention period was 3 weeks. The probiotic gums contained two strains of Lactobacilli reuteri (ATCC 55730 at a dose of 1 x 10(8) CFU/gum and ATCC PTA 5289 at a dose of 1 x 10(8) CFU/gum), and each pellet of the xylitol gum contained approximately 1.0 g xylitol as single sweetener. Pretreatment and posttreatment samples of stimulated whole saliva were collected and quantified for MS and LB with chair-side kits. A statistically significant reduction (p < 0.05) of salivary MS was displayed in group A and B after the intervention when compared with baseline. A similar but nonsignificant tendency was seen in group C. No alterations of salivary LB was demonstrated in any group. In conclusion, daily chewing on gums containing probiotic bacteria or xylitol reduced the levels of salivary MS in a significant way. However, a combination of probiotic and xylitol gums did not seem to enhance this effect.

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References

    1. Acta Odontol Scand. 2004 Jun;62(3):153-7 - PubMed
    1. Int J Paediatr Dent. 2007 Mar;17(2):79-85 - PubMed
    1. Pediatr Dent. 2006 Mar-Apr;28(2):154-63; discussion 192-8 - PubMed
    1. Eur J Oral Sci. 1997 Apr;105(2):170-7 - PubMed
    1. Acta Odontol Scand. 2005 Nov;63(6):317-20 - PubMed

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