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. 2007 Aug;17(4):217-20.
doi: 10.1007/s10286-007-0425-0. Epub 2007 Jun 15.

Sympathetic hyperactivity in patients with ulcerative colitis

Simona Maule  1 , Giulia Pierangeli, Sabina Cevoli, Daniela Grimaldi, Paolo Gionchetti, Giovanni Barbara, Fernando Rizzello, Vincenzo Stanghellini, Roberto Corinaldesi, Massimo Campieri, Pietro Cortelli
Affiliations

Sympathetic hyperactivity in patients with ulcerative colitis

Simona Maule et al. Clin Auton Res. 2007 Aug.

Abstract

Hypo and hyperactivity of the autonomic nervous system have been associated with chronic bowel inflammation diseases. We investigated the autonomic function in 11 patients with chronic ulcerative colitis (UC) and 17 healthy controls by means of cardiovascular autonomic tests and heart rate variability. Autonomic responses were normal in patients and controls. At rest, LF/HF ratios were significantly (P < 0.05) higher in chronic UC patients (2.4 +/- 1.6) compared to controls (1.2 +/- 1.0). Our results suggest a higher sympathetic tone at rest in patients with chronic UC.

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