doi: 10.1042/bj1510435.
Ontogenetic study of a myelin-derived fraction with 2':3'-cyclic nucleotide 3'-phosphodydrolase activity higher than that of myelin
- PMID: 175779
- PMCID: PMC1172375
- DOI: 10.1042/bj1510435
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Ontogenetic study of a myelin-derived fraction with 2':3'-cyclic nucleotide 3'-phosphodydrolase activity higher than that of myelin
Biochem J.
1975 Nov.
Abstract
A membrane fraction (SN 4), prepared from developing and mature rat forebrain by hypo-osmotic treatment of microsome (microsomal-fraction)-free myelin, appears to be closely related to the myelin-like fraction. Fraction SN 4 shows 2':3'-cyclic nucleotide 3'-phosphohydrolase activity higher than that of the parent myelin. Electrophoresis reveals a multitude of bands with the Wolfgram protein as the main component.
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