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Comment
. 2007 Jun;26(6):755-7.
doi: 10.1016/j.immuni.2007.06.003.

APRIL in the intestine: a good destination for immunoglobulin A(2)

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APRIL in the intestine: a good destination for immunoglobulin A(2)

Andrew J Macpherson et al. Immunity. 2007 Jun.
Free article

Abstract

Immunoglobulin A (IgA) confers mucosal protection against bacteria in the intestine. In this issue, He et al. (2007) find that bacterial molecules promote IgA(2) generation via the cytokine APRIL, produced by intestinal epithelial and dendritic cells.

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