APRIL in the intestine: a good destination for immunoglobulin A(2)
- PMID: 17582349
- DOI: 10.1016/j.immuni.2007.06.003
APRIL in the intestine: a good destination for immunoglobulin A(2)
Abstract
Immunoglobulin A (IgA) confers mucosal protection against bacteria in the intestine. In this issue, He et al. (2007) find that bacterial molecules promote IgA(2) generation via the cytokine APRIL, produced by intestinal epithelial and dendritic cells.
Comment on
-
Intestinal bacteria trigger T cell-independent immunoglobulin A(2) class switching by inducing epithelial-cell secretion of the cytokine APRIL.Immunity. 2007 Jun;26(6):812-26. doi: 10.1016/j.immuni.2007.04.014. Immunity. 2007. PMID: 17570691
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous
