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. 2007 Jun;55(6):461-6.

doi: 10.1016/j.phrs.2007.05.005. Epub 2007 May 18.

Happy birthday protein kinase C: past, present and future of a superfamily

Fiorenzo Battaini¹, Daria Mochly-Rosen

Affiliations

PMID: 17582783
PMCID: PMC2211741
DOI: 10.1016/j.phrs.2007.05.005

Happy birthday protein kinase C: past, present and future of a superfamily

Fiorenzo Battaini et al. Pharmacol Res. 2007 Jun.

. 2007 Jun;55(6):461-6.

doi: 10.1016/j.phrs.2007.05.005. Epub 2007 May 18.

Authors

Fiorenzo Battaini¹, Daria Mochly-Rosen

Affiliation

¹ Department of Neurosciences, Section of Pharmacology, University of Roma "Tor Vergata", School of Medicine, Roma, Italy. battaini@med.uniroma2.it

PMID: 17582783
PMCID: PMC2211741
DOI: 10.1016/j.phrs.2007.05.005

No abstract available

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Figures

Figure 1
Chronological studies on protein kinases C. The principal discoveries are reported focusing on pharmacological implications. The numbers in the circles indicate the reference citation. More details is provided in the text.

See this image and copyright information in PMC

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References

1. Takai Y, Kishimoto A, Inoue M, Nishizuka Y. Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum. J Biol Chem. 1977;252:7603–9. - PubMed
1. Inoue M, Kishimoto A, Takai Y, Nishizuka Y. Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain. J Biol Chem. 1977;252:7610–6. - PubMed
1. Takai Y, Kishimoto A, Iwasa Y, Kawahara Y, Mori T, Nishizuka Y. Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids. J Biol Chem. 1979;254:3692–5. - PubMed
1. Takai Y, Kishimoto A, Kikkawa U, Mori T, Nishizuka Y. Unsaturated diacylglycerol as a possible messenger for the activation of calcium-activated, phospholipid-dependent protein kinase system. Biochem Biophys Res Commun. 1979;91:1218–24. - PubMed
1. Hokin MR, Hokin LE. Enzyme secretion and the incorporation of P32 into phospholipids of pancreas slices. J Biol Chem. 1953;203:967–77. - PubMed

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