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Case Reports
. 2007 May;52(5):413-5.

Vitrification of human hatched blastocysts: a report of 4 cases

Kenichiro Hiraoka  1 , Kaori Hiraoka, Masayuki Kinutani, Kazuo Kinutani
Affiliations
  • PMID: 17583241
Case Reports

Vitrification of human hatched blastocysts: a report of 4 cases

Kenichiro Hiraoka et al. J Reprod Med. 2007 May.

Abstract

Background: Vitrification is a fairly well-established technique for cryopreservation of human zona-intact blastocysts. However, little is known about the efficacy of the vitrification technique for zona-free hatched blastocysts.

Case: A total of 4 hatched blastocysts from 4 healthy, infertile women undergoing in vitro fertilization were vitrified and warmed. All 4 hatched blastocysts expanded after warming and were transferred to 4 patients. Three of the women became clinically pregnant. Two healthy infants were born in 2 deliveries, and 1 pregnancy had progressed to 35 weeks at this writing.

Conclusion: Our results suggest that vitrification is a useful cryopreservation technique not only for zona-intact blastocysts but also for zona-free hatched blastocysts.

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