Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 2007 Jun;36(3):305-12.
doi: 10.1016/j.transci.2007.03.012. Epub 2007 Jun 20.

Automated red cell exchange procedures in patients with sickle cell disease

Ilknur Kozanoglu  1 , Can Boga, Hakan Ozdogu, Nurzen Sezgin, Ebru Kizilkilic, Mahmut Kural
Affiliations
Clinical Trial

Automated red cell exchange procedures in patients with sickle cell disease

Ilknur Kozanoglu et al. Transfus Apher Sci. 2007 Jun.

Abstract

In automated red cell exchange, about 60% of the patient's red blood cells are exchanged via apheresis for those of the donor. We report the outcome of 83 patients with sickle cell anemia (48 women and 35 men; age range, 17-49 years) who underwent a total of 196 apheresis procedures between December 2003 and October 2006 at our institution. We found that automated red cell exchange involving a reduced citrate infusion rate may provide benefit in the prevention or treatment of vaso-occlusive complications in patients with sickle cell disease and may be associated with protean effects on biochemical dynamics.

PubMed Disclaimer

Publication types

LinkOut - more resources