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. 1991 Sep;39(7):697-9.

[Characteristics of the first penicillinase-producing strains of Neisseria gonorrhoeae isolated in Tunisia]

[Article in French]
A Kechrid  1 , H Karoui, S Ben Rejeb
Affiliations
  • PMID: 1758722

[Characteristics of the first penicillinase-producing strains of Neisseria gonorrhoeae isolated in Tunisia]

[Article in French]
A Kechrid et al. Pathol Biol (Paris). 1991 Sep.

Abstract

The first penicillinase-producing strain of Neisseria gonorrhoeae was recently isolated in Tunisia (1989). Betalactamase production was detected by the iodometric agar test. Minimal inhibitory concentrations (MICs) in agar medium were 128 micrograms/ml for penicillin, ampicillin and amoxycillin. With the amoxycillin-clavulanic acid combination, MIC fell to 0.25 microgram/ml. An Asian-type plasmid pattern was evidenced in this strain, with presence of the 2.6 Mdal cryptic plasmid and of a 4.5 Mdal plasmid.

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