Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma
- PMID: 17594344
- DOI: 10.1111/j.1468-1331.2007.01842.x
Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma
Abstract
We report the case of a patient with acute lymphoblastic leukaemia who, after the initiation of treatment with vincristine (VCR), developed a fulminant motor polyradiculoneuropathy resembling an axonal variant of Guillain-Barré syndrome (GBS). This report shows that differentiating between axonal GBS and VCR-induced acute neurotoxicity may be a challenge for clinicians.
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