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Case Reports
. 2007 Jul;14(7):826-8.
doi: 10.1111/j.1468-1331.2007.01842.x.

Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma

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Case Reports

Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma

P González Pérez et al. Eur J Neurol. 2007 Jul.

Abstract

We report the case of a patient with acute lymphoblastic leukaemia who, after the initiation of treatment with vincristine (VCR), developed a fulminant motor polyradiculoneuropathy resembling an axonal variant of Guillain-Barré syndrome (GBS). This report shows that differentiating between axonal GBS and VCR-induced acute neurotoxicity may be a challenge for clinicians.

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