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Comment
. 2007 Jul 3;104(27):11125-6.
doi: 10.1073/pnas.0704764104. Epub 2007 Jun 26.

Stuffing a virus with DNA: dissecting viral genome packaging

Mark C Williams  1
Affiliations
Comment

Stuffing a virus with DNA: dissecting viral genome packaging

Mark C Williams. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Measurements of DNA packaging forces. (a) Schematic diagram of the optical tweezers experiment by Fuller et al. (1), in which the rate of DNA packaging by bacteriophage φ29 is measured as a function of force for high and low filling fractions. (b) Disagreement between theory and experiment may be due to the inability of the DNA to achieve an equilibrium structure during initial packaging. (c) Theoretical calculations of the internal packaging force assume an idealized DNA configuration.
See this image and copyright information in PMC

Comment on

References

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    1. Smith DE, Tans SJ, Smith SB, Grimes S, Anderson DL, Bustamante C. Nature. 2001;413:748–752. - PubMed

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