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. 2007 Aug;14(8):1053-5.
doi: 10.1128/CVI.00173-07. Epub 2007 Jun 27.

Seroprevalence of neutralizing antibodies to adenovirus type 5 among children in India: implications for recombinant adenovirus-based vaccines

Mohan Babu Appaiahgari  1 , Ravindra Mohan Pandey, Sudhanshu Vrati
Affiliations

Seroprevalence of neutralizing antibodies to adenovirus type 5 among children in India: implications for recombinant adenovirus-based vaccines

Mohan Babu Appaiahgari et al. Clin Vaccine Immunol. 2007 Aug.

Abstract

We determined the levels of adenovirus 5 (Ad5) neutralizing antibodies in children in India less than 2 years of age. The results clearly show an age-dependent increase in Ad5-specific immunity, with 7- to 12-month-old children having the lowest levels of Ad5 immunity. This opens up the scope for the use of recombinant Ad5-based vaccines in this age group.

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