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. 2007 Oct;101(10):1042-4.
doi: 10.1016/j.trstmh.2007.04.011. Epub 2007 Jun 29.

Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?

Carlos Eugênio Cavasini  1 , Luiz Carlos de Mattos, Alvaro Augusto D'Almeida Couto, Cláudia Regina Bonini-Domingos, Socrates Herrera Valencia, Wanessa Christina de Souza Neiras, Renata Tomé Alves, Andréa Regina Baptista Rossit, Lilian Castilho, Ricardo Luiz Dantas Machado
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Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?

Carlos Eugênio Cavasini et al. Trans R Soc Trop Med Hyg. 2007 Oct.

Abstract

We present evidence for Plasmodium vivax infection among Duffy blood group-negative inhabitants of Brazil. The P. vivax identification was determined by both genotypic and non-genotypic screening tests. The Duffy blood group was genotyped by PCR/RFLP and phenotyped using a microtyping kit. We detected two homozygous FY*B-33 carriers infected by P. vivax, whose circumsporozoite protein genotypes were VK210 and/or P. vivax-like. Additional efforts are necessary in order to clarify the evidence that P. vivax is being transmitted among Duffy blood group-negative patients from the Brazilian Amazon region.

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