Review
doi: 10.1111/j.1753-4887.2007.tb00329.x.
Obesity and nonalcoholic fatty liver disease
Affiliations
- PMID: 17605315
- DOI: 10.1111/j.1753-4887.2007.tb00329.x
Item in Clipboard
Review
Obesity and nonalcoholic fatty liver disease
Nutr Rev.
2007 Jun.
Abstract
With the increasing prevalence of obesity and type 2 diabetes mellitus in the general population, nonalcoholic fatty liver disease (NAFLD) has become a common diagnosis in clinical practice. Insulin resistance and oxidative stress play an important role in NAFLD development and progression. NAFLD affects one in three adults and one in 10 children/adolescents in the United States. Mortality in patients with NAFLD is significantly higher than in the general population of same age and gender with liver-related complications. Lifestyle intervention may improve NAFLD, but medications that increase insulin sensitivity and the antioxidant defenses in the liver deserve evaluation in carefully controlled trials.
Similar articles
-
GI epidemiology: nonalcoholic fatty liver disease.Aliment Pharmacol Ther. 2007 Apr 15;25(8):883-9. doi: 10.1111/j.1365-2036.2007.03246.x. Aliment Pharmacol Ther. 2007. PMID: 17402991 Review.
-
Nonalcoholic Fatty liver disease and obesity.Nutr Clin Pract. 2007 Feb;22(1):1-10. doi: 10.1177/011542650702200101. Nutr Clin Pract. 2007. PMID: 17242448 Review.
-
Nonalcoholic fatty liver disease as a complication of insulin resistance.Med Clin North Am. 2007 Nov;91(6):1125-49, ix. doi: 10.1016/j.mcna.2007.06.001. Med Clin North Am. 2007. PMID: 17964913 Review.
-
[Non-alcoholic fatty liver disease in children: a new complication of obesity].Ned Tijdschr Geneeskd. 2008 Nov 8;152(45):2443-7. Ned Tijdschr Geneeskd. 2008. PMID: 19051794 Review. Dutch.
-
Should nonalcoholic fatty liver disease be regarded as a hepatic illness only?World J Gastroenterol. 2007 Sep 21;13(35):4669-72. doi: 10.3748/wjg.v13.i35.4669. World J Gastroenterol. 2007. PMID: 17729388 Free PMC article. Review.
Cited by
-
Increased Circulating Levels of Alpha-Ketoglutarate in Morbidly Obese Women with Non-Alcoholic Fatty Liver Disease.PLoS One. 2016 Apr 28;11(4):e0154601. doi: 10.1371/journal.pone.0154601. eCollection 2016. PLoS One. 2016. PMID: 27123846 Free PMC article.
-
Awareness, management, and practice patterns of pediatric NAFLD by primary care physicians.Paediatr Child Health. 2021 Aug 27;27(2):93-98. doi: 10.1093/pch/pxab057. eCollection 2022 May. Paediatr Child Health. 2021. PMID: 35599680 Free PMC article.
-
Type 2 diabetes mellitus is associated with the fibrosis severity in patients with nonalcoholic fatty liver disease in a large retrospective cohort of Japanese patients.J Gastroenterol. 2014 Nov;49(11):1477-84. doi: 10.1007/s00535-013-0911-1. Epub 2013 Nov 26. J Gastroenterol. 2014. PMID: 24277052
-
Cordyceps militaris alleviates non-alcoholic fatty liver disease in ob/ob mice.Nutr Res Pract. 2014 Apr;8(2):172-6. doi: 10.4162/nrp.2014.8.2.172. Epub 2014 Mar 28. Nutr Res Pract. 2014. PMID: 24741401 Free PMC article.
-
Childhood Adiposity and Nonalcoholic Fatty Liver Disease in Adulthood.Pediatrics. 2017 Apr;139(4):e20162738. doi: 10.1542/peds.2016-2738. Pediatrics. 2017. PMID: 28356335 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
