doi: 10.1007/BF01940801.
Does an inhibitor of mitochondrial adenylate kinase also affect oxidative phosphorylation?
- PMID: 176055
- DOI: 10.1007/BF01940801
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Does an inhibitor of mitochondrial adenylate kinase also affect oxidative phosphorylation?
Experientia.
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Abstract
Adenylate kinase activity of intact mitochondria is strongly inhibited by Ap5A, i.e. p1,p5-Di (adenosine-5') pentaphosphate, whereas oxidative phosphorylation is not affected. Therefore, Ap5A is a useful tool to distinguish between oxidative and non oxidative ATP generating reactions.
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