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. 1976 Mar 15;32(3):298-9.
doi: 10.1007/BF01940801.

Does an inhibitor of mitochondrial adenylate kinase also affect oxidative phosphorylation?

J Lüstorff, E Schlimme

Does an inhibitor of mitochondrial adenylate kinase also affect oxidative phosphorylation?

J Lüstorff et al. Experientia. .

Abstract

Adenylate kinase activity of intact mitochondria is strongly inhibited by Ap5A, i.e. p1,p5-Di (adenosine-5') pentaphosphate, whereas oxidative phosphorylation is not affected. Therefore, Ap5A is a useful tool to distinguish between oxidative and non oxidative ATP generating reactions.

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