Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2007 Sep;51(9):3459-60.
doi: 10.1128/AAC.00791-07. Epub 2007 Jul 2.

Altered pharmacokinetics of voriconazole in a patient with liver cirrhosis

Case Reports

Altered pharmacokinetics of voriconazole in a patient with liver cirrhosis

Stefan Weiler et al. Antimicrob Agents Chemother. 2007 Sep.
No abstract available

PubMed Disclaimer

Figures

FIG. 1.
FIG. 1.
Voriconazole elimination after discontinuation of voriconazole. The dashed line indicates the concentration limit for favorable responses (9).

Similar articles

Cited by

References

    1. Den Hollander, J. G., C. van Arkel, B. J. Rijnders, P. J. Lugtenburg, S. de Marie, and M. D. Levin. 2006. Incidence of voriconazole hepatotoxicity during intravenous and oral treatment for invasive fungal infections. J. Antimicrob. Chemother. 57:1248-1250. - PubMed
    1. Denning, D. W., P. Ribaud, N. Milpied, D. Caillot, R. Herbrecht, E. Thiel, A. Haas, M. Ruhnke, and H. Lode. 2002. Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis. Clin. Infect. Dis. 34:563-571. - PubMed
    1. Khoschsorur, G., F. Fruehwirth, and S. Zelzer. 2005. Isocratic high-performance liquid chromatographic method with ultraviolet detection for simultaneous determination of levels of voriconazole and itraconazole and its hydroxy metabolite in human serum. Antimicrob. Agents Chemother. 49:3569-3571. - PMC - PubMed
    1. Kullberg, B. J., J. D. Sobel, M. Ruhnke, P. G. Pappas, C. Viscoli, J. H. Rex, J. D. Cleary, E. Rubinstein, L. W. Church, J. M. Brown, H. T. Schlamm, I. T. Oborska, F. Hilton, and M. R. Hodges. 2005. Voriconazole versus a regimen of amphotericin B followed by fluconazole for candidaemia in non-neutropenic patients: a randomised non-inferiority trial. Lancet 366:1435-1442. - PubMed
    1. Pascual, A. A., S. Bolay, and O. Marchetti. 2006. Monitoring of voriconazole (VRC) blood levels for prevention of serious neurological adverse events (SNAE). Int. J. Infect. Dis. 10:S67.