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Randomized Controlled Trial
. 2008 Jan;29(1):70-82.
doi: 10.1016/j.cct.2007.05.003. Epub 2007 Jun 2.

Safer choices 2: rationale, design issues, and baseline results in evaluating school-based health promotion for alternative school students

Susan R Tortolero  1 , Christine M Markham, Robert C Addy, Elizabeth R Baumler, Soledad Liliana Escobar-Chaves, Karen M Basen-Engquist, Nicole K McKirahan, Guy S Parcel
Affiliations
Randomized Controlled Trial

Safer choices 2: rationale, design issues, and baseline results in evaluating school-based health promotion for alternative school students

Susan R Tortolero et al. Contemp Clin Trials. 2008 Jan.

Abstract

Background: Students attending 'alternative' high schools form relatively small, highly mobile high-risk populations, presenting challenges for the design and implementation of HIV-, other STI-, and pregnancy-prevention interventions. This paper describes the rationale, study design, and baseline results for the Safer Choices 2 program.

Study design: Modified group-randomized intervention trial with cross-over of schools but not of students. The study cohort was defined a priori as those who completed the baseline measures and were still enrolled at the time of first follow-up. DESIGN RESULTS: Of 940 students initially enrolled in the study, 711 (76%) formed the study cohort. There were significant demographic differences between those included and those excluded from the study cohort in sex, age, sexual experience, experience with pregnancy, drug use, and some psychosocial measures. There were no significant differences between the intervention and control groups within the study cohort. The only significant difference between those students excluded from the intervention group and those excluded from the control group was reported age at first intercourse. BASELINE DATA RESULTS: Students (n=940) enrolled were predominately African-American (29.7%) and Hispanic (61.3%); 57.3% were female; 66% had ever had sex; and reported drug use in the previous 30 days ran from 4.3% (cocaine) to 26.9% (marijuana). Of the 627 sexually experienced, 41.8% reported their age at first intercourse as 13 years or younger; 28.5% reported ever being or having gotten someone pregnant; 74% reported sex in the past 3 months. Of the 464 sexually active in the last 3 months, 55.4% reported unprotected intercourse and 31.3% reported using drugs beforehand.

Conclusion: The cross-over design will provide a rigorous test of the intervention; however, loss to follow-up of this population can result in some selection bias. Students attending dropout prevention and recovery schools are at high risk for HIV, STIs, and pregnancy, and are in need of interventions.

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Figures

Figure 1
Figure 1
Planned Study Design: 1000 students, 10 schools
Figure 2
Figure 2
Summary of Recruitment and Retention of Sample and of Organization of Tables Reporting the Analyses Note: Vertical axis does not reflect time sequence
See this image and copyright information in PMC

References

    1. Weinstock H, Berman S, Cates W., Jr Sexually transmitted diseases among American youth: incidence and prevalence estimates. Perspectives on Sexual and Reproductive Health. 2000. pp. 6–10. Last updated: 2004. Available: < http://www.guttmacher.org/pubs/journals/3600604.html>. - PubMed
    1. DiLorenzo TA, Abramo DM, Hein K, et al. The evaluation of targeted outreach in an adolescent HIV/AIDS program. J Adolesc Health. 1993;14(4):301–306. - PubMed
    1. Jemmott JB, III, Jemmott LS, Fong GT. Reductions in HIV risk-associated sexual behaviors among black male adolescents: Effects of an AIDS prevention intervention. Am J Public Health. 1992;82(3):372–377. - PMC - PubMed
    1. MacKay AP, Fingerhut LA, Duran CR. Health, United States, 2000 . DHHS Publication No. (PHS) 2000-1232-1. Hyattsville, MD: National Center for Health Statistics; 2000. Jul, Adolescent Health Chartbook.
    1. National Institutes of Health. National Institute of Allergy and Infectious Diseases. HIV Infection in Adolescents and Young Adults in the U.S. fact sheet. Last updated: 2005 Jul. Available: < http://www.niaid.nih.gov/factsheets/hivadolescent.htm>.

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