Abyssomicins G and H and atrop-abyssomicin C from the marine Verrucosispora strain AB-18-032
- PMID: 17617698
- DOI: 10.1038/ja.2007.54
Abyssomicins G and H and atrop-abyssomicin C from the marine Verrucosispora strain AB-18-032
Abstract
Abyssomicin C is a complex polyketide-type antibiotic and the first natural inhibitor of the p-aminobenzoate biosynthesis produced by the marine Verrucosispora strain AB-18-032. We have now isolated three novel naturally produced abyssomicins, among them the even more active atrop-abyssomicin C. The chemical structures were elucidated by mass spectrometry and NMR spectroscopy.
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