Expression of Escherichia coli DcuS-R two-component regulatory system is regulated by the secondary internal promoter which is activated by CRP-cAMP
Affiliations
- PMID: 17618229
Item in Clipboard
Expression of Escherichia coli DcuS-R two-component regulatory system is regulated by the secondary internal promoter which is activated by CRP-cAMP
J Microbiol.
2007 Jun.
Free article
Abstract
The DcuS-R two-component system of Escherichia coli senses C4-dicarboxylates of the medium and regulates expression of the genes related to utilization of them. It is known that phospho-DcuR induces expression of genes such as the dcuB-fumB operon, the frdABCD operon, and the dctA gene. We analyzed promoters of the dcuS-R operon to elucidate the transcriptional regulation system. We found a novel internal promoter within the dcuS gene that is regulated by the transcriptional regulator, CRP-cAMP, in both aerobic and anaerobic conditions.
Similar articles
-
Cellular Concentrations of the Transporters DctA and DcuB and the Sensor DcuS of Escherichia coli and the Contributions of Free and Complexed DcuS to Transcriptional Regulation by DcuR.J Bacteriol. 2018 Jan 24;200(4):e00612-17. doi: 10.1128/JB.00612-17. Print 2018 Feb 15. J Bacteriol. 2018. PMID: 29203472 Free PMC article.
-
Regulation of Aerobic Succinate Transporter dctA of E. coli by cAMP-CRP, DcuS-DcuR, and EIIAGlc: Succinate as a Carbon Substrate and Signaling Molecule.Microb Physiol. 2024;34(1):108-120. doi: 10.1159/000538095. Epub 2024 Mar 1. Microb Physiol. 2024. PMID: 38432210
-
Identification and characterization of a two-component sensor-kinase and response-regulator system (DcuS-DcuR) controlling gene expression in response to C4-dicarboxylates in Escherichia coli.J Bacteriol. 1999 Feb;181(4):1238-48. doi: 10.1128/JB.181.4.1238-1248.1999. J Bacteriol. 1999. PMID: 9973351 Free PMC article.
-
Syn, anti, and finally both conformations of cyclic AMP are involved in the CRP-dependent transcription initiation mechanism in E. coli lac operon.Cell Biochem Funct. 2008 Jun;26(4):399-405. doi: 10.1002/cbf.1462. Cell Biochem Funct. 2008. PMID: 18338329 Review.
-
Sensing by the membrane-bound sensor kinase DcuS: exogenous versus endogenous sensing of C(4)-dicarboxylates in bacteria.Future Microbiol. 2010 Sep;5(9):1383-402. doi: 10.2217/fmb.10.103. Future Microbiol. 2010. PMID: 20860483 Review.
Cited by
-
Cellular Concentrations of the Transporters DctA and DcuB and the Sensor DcuS of Escherichia coli and the Contributions of Free and Complexed DcuS to Transcriptional Regulation by DcuR.J Bacteriol. 2018 Jan 24;200(4):e00612-17. doi: 10.1128/JB.00612-17. Print 2018 Feb 15. J Bacteriol. 2018. PMID: 29203472 Free PMC article.
-
Identification and characterization of novel phosphate regulon genes, ecs0540-ecs0544, in Escherichia coli O157:H7.Mol Genet Genomics. 2010 Sep;284(3):197-205. doi: 10.1007/s00438-010-0559-y. Epub 2010 Jul 17. Mol Genet Genomics. 2010. PMID: 20640580
-
Identification of PhoB binding sites of the yibD and ytfK promoter regions in Escherichia coli.J Microbiol. 2011 Apr;49(2):285-9. doi: 10.1007/s12275-011-0360-6. Epub 2011 May 3. J Microbiol. 2011. PMID: 21538251
-
TP0262 is a modulator of promoter activity of tpr Subfamily II genes of Treponema pallidum ssp. pallidum.Mol Microbiol. 2009 Jun;72(5):1087-99. doi: 10.1111/j.1365-2958.2009.06712.x. Epub 2009 Apr 30. Mol Microbiol. 2009. PMID: 19432808 Free PMC article.
-
Alternative promoters in the pst operon of Escherichia coli.Mol Genet Genomics. 2010 Dec;284(6):489-98. doi: 10.1007/s00438-010-0584-x. Epub 2010 Oct 21. Mol Genet Genomics. 2010. PMID: 20963440
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases
Research Materials
Miscellaneous
