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. 2007 Jun;45(3):234-40.

Expression of Escherichia coli DcuS-R two-component regulatory system is regulated by the secondary internal promoter which is activated by CRP-cAMP

Tomoya Oyamada  1 , Katsushi Yokoyama, Michiko Morinaga, Masashi Suzuki, Kozo Makino
Affiliations
  • PMID: 17618229
Free article

Expression of Escherichia coli DcuS-R two-component regulatory system is regulated by the secondary internal promoter which is activated by CRP-cAMP

Tomoya Oyamada et al. J Microbiol. 2007 Jun.
Free article

Abstract

The DcuS-R two-component system of Escherichia coli senses C4-dicarboxylates of the medium and regulates expression of the genes related to utilization of them. It is known that phospho-DcuR induces expression of genes such as the dcuB-fumB operon, the frdABCD operon, and the dctA gene. We analyzed promoters of the dcuS-R operon to elucidate the transcriptional regulation system. We found a novel internal promoter within the dcuS gene that is regulated by the transcriptional regulator, CRP-cAMP, in both aerobic and anaerobic conditions.

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