Review
doi: 10.1016/j.cmet.2007.06.009.
TOR signaling and S6 kinase 1: Yeast catches up
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- PMID: 17618850
- DOI: 10.1016/j.cmet.2007.06.009
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Review
TOR signaling and S6 kinase 1: Yeast catches up
Cell Metab.
2007 Jul.
Free article
Abstract
Conservation of the rapamycin-sensitive TOR signaling network among eukaryotes has been instrumental to the rapid progress made in this field in recent years. A recent report in Molecular Cell (Urban et al., 2007) now extends this conservation to include Sch9, an AGC protein kinase family member from S. cerevisiae, which appears to be the long sought after yeast ortholog of mammalian S6 kinase 1 (S6K1) and a direct target for the rapamycin-sensitive TOR complex I.
Comment on
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Sch9 is a major target of TORC1 in Saccharomyces cerevisiae.Mol Cell. 2007 Jun 8;26(5):663-74. doi: 10.1016/j.molcel.2007.04.020. Mol Cell. 2007. PMID: 17560372
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