Review
doi: 10.1248/yakushi1947.111.9_488.
[Mammalian cellular phospholipases A2 and their physiological roles]
[Article in
Japanese]
Affiliations
- PMID: 1762050
- DOI: 10.1248/yakushi1947.111.9_488
Item in Clipboard
Review
[Mammalian cellular phospholipases A2 and their physiological roles]
[Article in
Japanese]
Yakugaku Zasshi.
1991 Sep.
Abstract
Phospholipase A2 hydrolyzes the ester linkage at sn-2 of glycerophospholipids and is thought to function as a key enzyme in generation of variety of bioactive mediators, such as prostaglandins and platelet-activating factor. In the present review, recent studies on two kinds of cellular phospholipases A2, 14 kDa group II phospholipase A2 and arachidonate-preferentially hydrolyzing phospholipase A2, will be summarized.
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