Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Jul;77(1):188-91.

An eight-year study of epidemiologic features of enterovirus 71 infection in Taiwan

Shou-Chien Chen  1 , Hsiao-Ling Chang, Tsong-Rong Yan, Yan-Tzong Cheng, Kow-Tong Chen
Affiliations
  • PMID: 17620652

An eight-year study of epidemiologic features of enterovirus 71 infection in Taiwan

Shou-Chien Chen et al. Am J Trop Med Hyg. 2007 Jul.

Abstract

In 1998, an epidemic of enterovirus 71 (EV 71) infection occurred in Taiwan. The purpose of this study was to assess the epidemiology of EV 71 infection in Taiwan. Between March 1998 and December 2005, a total of 1,548 severe cases of hand-foot-mouth disease and herpangina (HFMD/HA) was reported to the Center for Disease Control in Taiwan. A seasonal variation in number of severe cases was observed, with the annual peak in second quarter. Deaths from severe HFMD/HA varied from year to year (chi(2) for trend = 6.781, P = 0.009). Most (92%) cases occurred in children </= 4 years of age. Children infected with EV 71 had higher risk of pulmonary edema/hemorrhage and encephalitis than those not infected. Infection with EV 71 has emerged as an important infectious disease causing serious clinical illness and deaths of young children. Vaccine development is recommended to prevent future EV 71 infections.

PubMed Disclaimer