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Clinical Trial
. 2007;28(3):214-6.

Investigation of Keyes skin biopsy instrument for cervical biopsy procedures versus Kevorkian biopsy forceps

S Ayas  1 , I Aköz, A Gürbüz, E Eskicirak, H Cetiner, A Karateke
Affiliations
  • PMID: 17624090
Clinical Trial

Investigation of Keyes skin biopsy instrument for cervical biopsy procedures versus Kevorkian biopsy forceps

S Ayas et al. Eur J Gynaecol Oncol. 2007.

Abstract

Objective: We aimed to investigate the utility and efficacy of the Keyes skin biopsy instrument for cervical biopsy procedures.

Material and methods: A prospective clinical trial was conducted on 50 women with cervical lesions. Colposcopy-guided cervical biopsies were collected using a Keyes biopsy punch and a Kevorkian biopsy forceps and the two methods were compared with definitive histopathological examination of the specimens obtained by the loop electrosurgical excision procedure (LEEP), conization or hysterectomy.

Results: There were no differences in speed of collection, diagnostic value of specimens, complication rates, or sample quality. The sensitivity, specificity, positive and negative predictivity of specimens were all 100% for both methods.

Conclusions: The Keyes biopsy punch was found to be a safe, rapid and accurate diagnostic tool in cervical biopsy procedures. Based on the results of this study, the use of a Keyes punch instrument can be recommended as an alternative to other cervical biopsy methods.

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