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Review

. 2007:3:126.

doi: 10.1038/msb4100169. Epub 2007 Jul 10.

Principles of optimal metabolic network operation

Affiliations

PMID: 17625514
PMCID: PMC1949038
DOI: 10.1038/msb4100169

Review

Principles of optimal metabolic network operation

Jens Nielsen. Mol Syst Biol. 2007.

. 2007:3:126.

doi: 10.1038/msb4100169. Epub 2007 Jul 10.

Author

Affiliation

¹ Center for Microbial Biotechnology, Technical University of Denmark, Lyngby, Denmark.

PMID: 17625514
PMCID: PMC1949038
DOI: 10.1038/msb4100169

No abstract available

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Comment on

Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli.
Schuetz R, Kuepfer L, Sauer U. Schuetz R, et al. Mol Syst Biol. 2007;3:119. doi: 10.1038/msb4100162. Epub 2007 Jul 10. Mol Syst Biol. 2007. PMID: 17625511 Free PMC article.

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References

1. Bro C, Regenberg B, Forster J, Nielsen J (2006) In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production. Metab Eng 8: 102–111 - PubMed
1. Edwards JS, Ibarra RU, Palsson BO (2001) In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data. Nat Biotechnol 19: 125–130 - PubMed
1. Fischer E, Sauer U (2005) Large-scale in vivo flux analysis shows rigidity and suboptimal performance of Bacillus subtilis metabolism. Nat Genet 37: 636–640 - PubMed
1. Ibarra RU, Edwards JS, Palsson BO (2002) Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth. Nature 420: 186–189 - PubMed
1. Nielsen J (2003) It is all about metabolic fluxes. J Bacteriol 85: 7031–7035 - PMC - PubMed

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