Principles of optimal metabolic network operation
- PMID: 17625514
- PMCID: PMC1949038
- DOI: 10.1038/msb4100169
Principles of optimal metabolic network operation
Comment on
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Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli.Mol Syst Biol. 2007;3:119. doi: 10.1038/msb4100162. Epub 2007 Jul 10. Mol Syst Biol. 2007. PMID: 17625511 Free PMC article.
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- Fischer E, Sauer U (2005) Large-scale in vivo flux analysis shows rigidity and suboptimal performance of Bacillus subtilis metabolism. Nat Genet 37: 636–640 - PubMed
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- Ibarra RU, Edwards JS, Palsson BO (2002) Escherichia coli K-12 undergoes adaptive evolution to achieve in silico predicted optimal growth. Nature 420: 186–189 - PubMed
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