A review of the efficacy and safety of devil's claw for pain associated with degenerative musculoskeletal diseases, rheumatoid, and osteoarthritis
- PMID: 17627199
- DOI: 10.1097/01.HNP.0000280932.65581.72
A review of the efficacy and safety of devil's claw for pain associated with degenerative musculoskeletal diseases, rheumatoid, and osteoarthritis
Abstract
Harpagophytum procumbens, known as devil's claw, has been used traditionally for the treatment of pain, fevers, and dyspepsia. Recently, it has become popular for the treatment of rheumatoid and osteoarthritis. Studies have yet to establish a clear mechanism of action; however, current research is focusing on pro-inflammatory mediators as well as on potential antioxidant characteristics.
Similar articles
-
Devil's Claw (Harpagophytum procumbens) as a treatment for osteoarthritis: a review of efficacy and safety.J Altern Complement Med. 2006 Dec;12(10):981-93. doi: 10.1089/acm.2006.12.981. J Altern Complement Med. 2006. PMID: 17212570 Review.
-
Harpagophytum procumbens (devil's claw). Monograph.Altern Med Rev. 2008 Sep;13(3):248-52. Altern Med Rev. 2008. PMID: 18950251 No abstract available.
-
Treatment of patients with arthrosis of hip or knee with an aqueous extract of devil's claw (Harpagophytum procumbens DC.).Phytother Res. 2003 Dec;17(10):1165-72. doi: 10.1002/ptr.1322. Phytother Res. 2003. PMID: 14669250 Clinical Trial.
-
A review of the biological and potential therapeutic actions of Harpagophytum procumbens.Phytother Res. 2007 Mar;21(3):199-209. doi: 10.1002/ptr.2029. Phytother Res. 2007. PMID: 17128436 Review.
-
[Therapy of degenerative diseases of the musculoskeletal system with South African devil's claw (Harpagophytum procumbens DC)].Wien Med Wochenschr. 1999;149(8-10):254-7. Wien Med Wochenschr. 1999. PMID: 10483693 Review. German.
Cited by
-
Phytochemical Analysis and Anti-Inflammatory and Anti-Osteoarthritic Bioactive Potential of Verbascum thapsus L. (Scrophulariaceae) Leaf Extract Evaluated in Two In Vitro Models of Inflammation and Osteoarthritis.Molecules. 2021 Sep 5;26(17):5392. doi: 10.3390/molecules26175392. Molecules. 2021. PMID: 34500824 Free PMC article.
-
Complementary and alternative medicine use in rheumatoid arthritis: proposed mechanism of action and efficacy of commonly used modalities.Rheumatol Int. 2010 Mar;30(5):571-86. doi: 10.1007/s00296-009-1206-y. Epub 2009 Oct 30. Rheumatol Int. 2010. PMID: 19876631 Review.
-
A Panoramic Review on the Management of Rheumatoid Arthritis through Herbalism.Curr Rheumatol Rev. 2025;21(1):4-24. doi: 10.2174/0115733971279100240328063232. Curr Rheumatol Rev. 2025. PMID: 38591212 Review.
-
Osteogenic and Anti-Inflammatory Behavior of Injectable Calcium Phosphate Loaded with Therapeutic Drugs.Nanomaterials (Basel). 2020 Sep 3;10(9):1743. doi: 10.3390/nano10091743. Nanomaterials (Basel). 2020. PMID: 32899225 Free PMC article.
-
Association between Fas/FasL gene polymorphism and musculoskeletal degenerative diseases: a meta-analysis.BMC Musculoskelet Disord. 2018 May 7;19(1):137. doi: 10.1186/s12891-018-2057-z. BMC Musculoskelet Disord. 2018. PMID: 29734947 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical