Tumor suppression by DNA base excision repair
- PMID: 17627584
- DOI: 10.2174/138955707781024544
Tumor suppression by DNA base excision repair
Abstract
Base excision repair (BER) is the main pathway for repair of endogenous DNA damage. It was expected that different tumor types could derive from BER defects but to date this link is elusive. In vitro and molecular epidemiology studies may be used to unravel this issue.
Similar articles
-
Base excision repair and cancer.Cancer Lett. 2012 Dec 31;327(1-2):73-89. doi: 10.1016/j.canlet.2011.12.038. Epub 2012 Jan 15. Cancer Lett. 2012. PMID: 22252118 Free PMC article. Review.
-
Commentary: DNA base excision repair defects in human pathologies.Free Radic Res. 2004 Oct;38(10):1037-54. doi: 10.1080/10715760400011445. Free Radic Res. 2004. PMID: 15512792 Review.
-
Estimating the effect of human base excision repair protein variants on the repair of oxidative DNA base damage.Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):1000-8. doi: 10.1158/1055-9965.EPI-05-0817. Cancer Epidemiol Biomarkers Prev. 2006. PMID: 16702383
-
Divide and conquer: nucleotide excision repair battles cancer and ageing.Curr Opin Cell Biol. 2003 Apr;15(2):232-40. doi: 10.1016/s0955-0674(03)00018-8. Curr Opin Cell Biol. 2003. PMID: 12648680 Review.
-
Genome instability and DNA damage accumulation in gene-targeted mice.Neuroscience. 2007 Apr 14;145(4):1309-17. doi: 10.1016/j.neuroscience.2006.10.059. Epub 2007 Jan 9. Neuroscience. 2007. PMID: 17218062 Review.
Cited by
-
Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis.Exp Mol Pathol. 2008 Apr;84(2):102-12. doi: 10.1016/j.yexmp.2007.12.003. Epub 2008 Jan 11. Exp Mol Pathol. 2008. PMID: 18280469 Free PMC article.
-
XRCC1 and base excision repair balance in response to nitric oxide.DNA Repair (Amst). 2011 Dec 10;10(12):1282-93. doi: 10.1016/j.dnarep.2011.10.008. Epub 2011 Oct 29. DNA Repair (Amst). 2011. PMID: 22041025 Free PMC article.
-
Deoxyinosine repair in nuclear extracts of human cells.Cell Biosci. 2015 Sep 8;5:52. doi: 10.1186/s13578-015-0044-8. eCollection 2015. Cell Biosci. 2015. PMID: 26357532 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources