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. 2007 Oct;24(4):415-7.
doi: 10.1016/j.bioeng.2007.05.003. Epub 2007 May 31.

Interphase chromosome-specific multicolor banding (ICS-MCB): a new tool for analysis of interphase chromosomes in their integrity

Ivan Y Iourov  1 , Thomas Liehr, Svetlana G Vorsanova, Yuri B Yurov
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Interphase chromosome-specific multicolor banding (ICS-MCB): a new tool for analysis of interphase chromosomes in their integrity

Ivan Y Iourov et al. Biomol Eng. 2007 Oct.

Abstract

Biomedical research of interphase chromosomes in their integrity is hindered by technical limitations. We introduce a technology using microdissection-based engineering of DNA probes and fluorescence multicolor chromosome banding that allows studying interphase chromosome organization, numbers and rearrangements in somatic cells.

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