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Comment

. 2007 Sep 1;583(Pt 2):419-20.

doi: 10.1113/jphysiol.2007.140269. Epub 2007 Jul 12.

Repolarization gradients and arrhythmogenicity in the murine heart

Matthew J Killeen¹, Ian N Sabir

Affiliations

PMID: 17627980
PMCID: PMC2277013
DOI: 10.1113/jphysiol.2007.140269

Comment

Repolarization gradients and arrhythmogenicity in the murine heart

Matthew J Killeen et al. J Physiol. 2007.

. 2007 Sep 1;583(Pt 2):419-20.

doi: 10.1113/jphysiol.2007.140269. Epub 2007 Jul 12.

Authors

Matthew J Killeen¹, Ian N Sabir

Affiliation

¹ Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK. mjk42@cam.ac.uk

PMID: 17627980
PMCID: PMC2277013
DOI: 10.1113/jphysiol.2007.140269

No abstract available

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Comment on

Dispersion of repolarization and refractoriness are determinants of arrhythmia phenotype in transgenic mice with long QT.
London B, Baker LC, Petkova-Kirova P, Nerbonne JM, Choi BR, Salama G. London B, et al. J Physiol. 2007 Jan 1;578(Pt 1):115-29. doi: 10.1113/jphysiol.2006.122622. Epub 2006 Nov 16. J Physiol. 2007. PMID: 17110412 Free PMC article.

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References

1. Killeen MJ, Thomas G, Gurung IS, Goddard CA, Fraser JA, Mahaut-Smith MP, Colledge WH, Grace AA, Huang CL. Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart. Acta Physiol (Oxf) 2007;189:33–46. - PMC - PubMed
1. London B. Cardiac arrhythmias: from (transgenic) mice to men. J Cardiovasc Electrophysiol. 2001;12:1089–1091. - PubMed
1. London B, Baker LC, Petkova-Kirova P, Nerbonne JM, Choi BR, Salama G. Dispersion of repolarization and refractoriness are determinants of arrhythmia phenotype in transgenic mice with long QT. J Physiol. 2007;578:115–129. - PMC - PubMed
1. Papadatos GA, Wallerstein PM, Head CE, Ratcliff R, Brady PA, Benndorf K, Saumarez RC, Trezise AE, Huang CL, Vandenberg JI, Colledge WH, Grace AA. Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a. Proc Natl Acad Sci U S A. 2002;99:6210–6215. - PMC - PubMed
1. Sabir IN, Fraser JA, Killeen MJ, Grace AA, Huang CL. The contribution of refractoriness to arrhythmic substrate in hypokalemic Langendorff-perfused murine hearts. Pflugers Arch. 2007;454:209–222. - PMC - PubMed

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