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. 2007 Sep;78(6):426-9.
doi: 10.1016/j.fitote.2007.02.020. Epub 2007 May 23.

Antiproliferative activity of Citrus juices and HPLC evaluation of their flavonoid composition

Lorenzo Camarda  1 , Vita Di Stefano, Sergio Fatta Del Bosco, Domenico Schillaci
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Antiproliferative activity of Citrus juices and HPLC evaluation of their flavonoid composition

Lorenzo Camarda et al. Fitoterapia. 2007 Sep.

Abstract

The antiproliferative activity of fresh fruit juices extracted from Citrus sinensis (cv. Washington Navel and cv. Sanguinello), C. deliciosa cv. Avana, C. clementina cv. Nules, C. aurantium subsp. myrtifolia , was evaluated against K562 (human chronic myelogenous leukemia), HL-60 (human leukemia) and MCF-7 (human breast adenocarcinoma) cell lines. All the juices tested showed antiproliferative activity. Moreover, the pattern of the main flavanone compounds in the juices has been determined by HPLC analysis.

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