Infectivity, oncogenicity and transforming ability of BK virus and BK virus DNA
- PMID: 176315
- DOI: 10.1099/0022-1317-30-3-371
Infectivity, oncogenicity and transforming ability of BK virus and BK virus DNA
Abstract
The human papovavirus, BK, appeared weakly oncogenic in newborn hamsters and was able to induce in vitro transformation of rat kidney cells. The infectivity of BK virus DNA was determined by employing the DEAE-dextran method. In human embryonic cells the infectivity was approx. 10(5) p.f.u./mug of DNA. The transforming ability of BK virus in primary rat kidney cells was measured by employing the calcium method and appeared to vary from 1 to 10 foci per mug of DNA.
MeSH terms
LinkOut - more resources
Full Text Sources
