Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2008 May;136(5):621-7.
doi: 10.1017/S095026880700917X. Epub 2007 Jul 16.

High burden of invasive beta-haemolytic streptococcal infections in Fiji

A C Steer  1 , A J W Jenney, F Oppedisano, M R Batzloff, J Hartas, J Passmore, F M Russell, J H H Kado, J R Carapetis
Affiliations
Comparative Study

High burden of invasive beta-haemolytic streptococcal infections in Fiji

A C Steer et al. Epidemiol Infect. 2008 May.

Abstract

We undertook a 5-year retrospective study of group A streptococcal (GAS) bacteraemia in Fiji, supplemented by a 9-month detailed retrospective study of beta-haemolytic streptococcal (BHS) infections. The all-age incidence of GAS bacteraemia over 5 years was 11.6/100,000. Indigenous Fijians were 4.7 times more likely to present with invasive BHS disease than people of other ethnicities, and 6.4 times more likely than Indo-Fijians. The case-fatality rate for invasive BHS infections was 28%. emm-typing was performed on 23 isolates: 17 different emm-types were found, and the emm-type profile was different from that found in industrialized nations. These data support the contentions that elevated rates of invasive BHS and GAS infections are widespread in developing countries, and that the profile of invasive organisms in these settings reflects a wide diversity of emm-types and a paucity of types typically found in industrialized countries.

PubMed Disclaimer

References

    1. Lamagni T et al. The epidemiology of severe Streptococcus pyogenes associated disease in Europe. Eurosurveillance. 2005;10:179–184. - PubMed
    1. Rogers S et al. Strain prevalence, rather than innate virulence potential, is the major factor responsible for an increase in serious group a streptococcus infections. Journal of Infectious Diseases. 2007;195:1625–1633. - PubMed
    1. Lopardo H et al. Six-month multicenter study on invasive infections due to Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis in Argentina. Journal of Clinical Microbiology. 2005;43:802–807. - PMC - PubMed
    1. Ikebe T et al. Surveillance of severe invasive group-G streptococcal infections and molecular typing of the isolates in Japan. Epidemiology and Infection. 2004;132:145–149. - PMC - PubMed
    1. O'Brien K et al. Epidemiology of invasive group A streptococcus disease in the United States, 1995–1999. Clinical Infectious Diseases. 2002;35:268–276. - PubMed

Publication types

MeSH terms