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Review
. 2007 May-Jun;25(3):457-60.

Propionibacterium acnes and SAPHO syndrome: a case report and literature review

M Colina  1 , A Lo Monaco, M Khodeir, F Trotta
Affiliations
  • PMID: 17631745
Review

Propionibacterium acnes and SAPHO syndrome: a case report and literature review

M Colina et al. Clin Exp Rheumatol. 2007 May-Jun.

Abstract

Objective: To describe the presence of Propionibacterium acnes (P. acnes) in a series of patients with SAPHO syndrome in which a bone biopsy has been carried out and to discuss the results comparing them to the data described in the literature.

Methods: In 6 out of 56 patients with SAPHO syndrome, a bone biopsy from osteitic lesion was carried out. This invasive investigation was performed only in those cases in which it was necessary to clarify the diagnosis.

Results: Of the 6 biopsies processed, P. acnes was isolated in only one case. No other infectious agents were identified.

Conclusion: P. acnes is not often found in bone lesions of SAPHO syndrome. A bone biopsy may represent a procedure useful for corroborating the diagnosis or for excluding other diseases only in specific cases.

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