Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Jul 16:4:16.
doi: 10.1186/1742-6405-4-16.

HIV-associated adipose redistribution syndrome (HARS): definition, epidemiology and clinical impact

Kenneth Lichtenstein  1 , Ashok Balasubramanyam, Rajagopal Sekhar, Eric Freedland
Affiliations

HIV-associated adipose redistribution syndrome (HARS): definition, epidemiology and clinical impact

Kenneth Lichtenstein et al. AIDS Res Ther. .

Abstract

A segment of the HIV infected population develops abnormal and excessive accumulation of adipose tissue in the trunk, including accumulation of visceral (deep abdominal) adipose tissue. This condition, known as HIV-related adipose redistribution syndrome (HARS), may also be accompanied by fat accumulation in the upper back/neck (dorsocervical region) and/or depletion of subcutaneous adipose tissue from the abdomen, face, limbs, or buttocks. HARS is estimated to occur in up to 32% of patients and is associated with health risks similar to those of metabolic syndrome. Techniques to detect and measure HARS include physician and patient assessments and radiologic or anthropometric methods.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Garcia-Viejo MA, Ruiz M, Martinez E. Strategies for treating HIV-related lipodystrophy. Expert Opin Investig Drugs. 2001;10:1443–1456. doi: 10.1517/13543784.10.8.1443. - DOI - PubMed
    1. Powderly WG. Long-term exposure to lifelong therapies. J Acquir Immune Defic Syndr. 2002;29:S28–40. - PubMed
    1. Carr A, Samaras K, Burton S, Law M, Freund J, Chisholm DJ, Cooper DA. A syndrome of peripheral lipodystrophy, hyperlipidaemia and insulin resistance in patients receiving HIV protease inhibitors. AIDS. 1998;12:F51–58. doi: 10.1097/00002030-199807000-00003. - DOI - PubMed
    1. Engelson ES, Kotler DP, Tan Y, Agin D, Wang J, Pierson RN, Jr, Heymsfield SB. Fat distribution in HIV-infected patients reporting truncal enlargement quantified by whole-body magnetic resonance imaging. Am J Clin Nutr. 1999;69:1162–1169. - PubMed
    1. Herry I, Bernand L, de Truchis P, Perronne C. Hypertrophy of the breasts in a patient treated with indinavir. Clin Infect Dis. 1997;25:937–938. - PubMed

LinkOut - more resources