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. 2007 Sep;33(5):1086-92.
doi: 10.1093/schbul/sbm082. Epub 2007 Jul 18.

Identifying unmet therapeutic domains in schizophrenia patients: the early contributions of Wayne Fenton from Chestnut Lodge

Thomas H McGlashan  1 , William T Carpenter
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Identifying unmet therapeutic domains in schizophrenia patients: the early contributions of Wayne Fenton from Chestnut Lodge

Thomas H McGlashan et al. Schizophr Bull. 2007 Sep.

Abstract

Wayne Fenton, MD, died on September 3, 2006, while giving emergency clinical care. His leadership at National Institute of Mental Health provided a framework for therapeutic discovery. He crafted a new approach to psychosis based on poor functional outcomes and the psychopathology domains underlying long-term morbidity. His research and clinical observations during his career at the Chestnut Lodge clarified the unmet therapeutic needs in schizophrenia and provided the foundation for his vision. The results have radically changed the paradigm for discovery with emphasis on impaired cognition and negative symptom psychopathology.

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References

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    1. McGlashan TH. The Chestnut Lodge follow-up study: II: long-term outcome of schizophrenia and the affective disorders. Arch Gen Psychiatry. 1984;41:585–601. - PubMed
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