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Meta-Analysis
. 2007 Jul 18;2007(3):CD001825.
doi: 10.1002/14651858.CD001825.pub2.

Closed suction surgical wound drainage after orthopaedic surgery

Affiliations
Meta-Analysis

Closed suction surgical wound drainage after orthopaedic surgery

M J Parker et al. Cochrane Database Syst Rev. .

Abstract

Background: Closed suction drainage systems are frequently used to drain fluids, particularly blood, from surgical wounds. The aim of these systems is to reduce the occurrence of wound haematomas and infection.

Objectives: To evaluate the effectiveness of closed suction drainage systems for orthopaedic surgery.

Search strategy: We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (March 2006), and contacted the Cochrane Wounds Group. We also searched the Cochrane Central Register of Controlled Trials (The Cochrane Library 2006, Issue 1), and MEDLINE (1966 to March 2006). Articles of all languages were considered.

Selection criteria: All randomised or quasi-randomised trials comparing the use of closed suction drainage systems with no drainage systems for all types of elective and emergency orthopaedic surgery.

Data collection and analysis: Two authors independently assessed trial quality, using a nine item scale, and extracted data. Where appropriate, results of comparable studies were pooled.

Main results: Thirty-six studies involving 5464 participants with 5697 surgical wounds were identified. The types of surgery involved were hip and knee replacement, shoulder surgery, hip fracture surgery, spinal surgery, cruciate ligament reconstruction, open meniscectomy and fracture fixation surgery. Pooling of results indicated no statistically significant difference in the incidence of wound infection, haematoma, dehiscence or re-operations between those allocated to drains and the un-drained wounds. Blood transfusion was required more frequently in those who received drains. The need for reinforcement of wound dressings and the occurrence of bruising were more common in the group without drains.

Authors' conclusions: There is insufficient evidence from randomised trials to support the routine use of closed suction drainage in orthopaedic surgery. Further randomised trials with larger patient numbers are required for different operations before definite conclusions can be made for all types of orthopaedic operations.

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Conflict of interest statement

None known.

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References

References to studies included in this review

Adalberth 1998 {published data only}
    1. Adalberth G, Bystrom S, Kolstad K, Mallmin H, Milbrink J. Postoperative drainage for knee arthroplasty is not necessary; a randomized study of 90 patients. Acta Orthopaedica Scandinavica 1998;69(5):475‐8. - PubMed
Blank 2003 {published data only}
    1. Blank J, Flynn JM, Bronson W, Ellman P, Pill SG, Lou JE, et al. The use of postoperative subcutaneous closed suction drainage after posterior spinal fusion in adolescents with idiopathic scoliosis. Journal of Spinal Disorders & Techniques 2003;16(6):508‐12. - PubMed
Browett 1978 {published data only}
    1. Browett JP, Gibbs AN, Copeland SA, Deliss LJ. The use of suction drainage in the operation of meniscectomy. Journal of Bone and Joint Surgery. British Volume 1978;60(4):516‐9. - PubMed
Brown 2004 {published data only}
    1. Brown MD, Brookfield KF. A randomized study of closed wound suction drainage for extensive lumbar spine surgery. Spine 2004;29(10):1066‐8. - PubMed
Cobb 1990 {published data only}
    1. Cobb JC. Why use drains? [abstract]. Journal of Bone and Joint Surgery. British Volume 1989;71(5):873.
    1. Cobb JP. Why use drains?. Journal of Bone and Joint Surgery. British Volume 1990;72(6):993‐5. - PubMed
Confalonieri 2004 {published data only}
    1. Confalonieri N, Manzotti A, Motavalli K, Fascia M. What is the closed suction drain role following unicompartmental knee replacement? A prospective randomised study. Journal of Bone and Joint Surgery. British Volume 2006;88‐B(Supp I):106.
    1. Confalonieri N, Manzotti A, Pullen C. Is closed‐suction drain necessary in unicompartmental knee replacement? A prospective randomised study. The Knee 2004;11(5):399‐402. - PubMed
Crevoisier 1998 {published data only}
    1. Crevoisier XM, Reber P, Noesberger B. Is suction drainage necessary after total joint arthroplasty? A prospective study. Archives of Orthopaedic and Trauma Surgery 1998;117(3):121‐4. - PubMed
Dhawan 2003 {published data only}
    1. Dhawan A, Doukas WC, Papazis JA, Scoville CR. Effect of drain use in the early postoperative period after arthroscopically assisted anterior cruciate ligament reconstruction with bone‐patellar tendon‐bone graft. American Journal of Sports Medicine 2003;31(3):419‐24. - PubMed
Duranthon 2000 {published data only}
    1. Duranthon LD, Grimberg J, Vandenbussche E, Mondoloni B, Augereau P. Effectiveness of postoperative drainage after bipolar sealed endoprosthetic arthroplasty for femur neck fracture. Results of a prospective randomized study of 86 cases]. [French [L'efficacite du drainage postoperatoire apres arthroplastie par prothese intermediaire scellee pour fracture du col du femur; resultats d'une etude prospective randomisee de 86 cas]. Revue de Chirurgie Orthopedique et Reparatrice de l'Appareil Moteur 2000;86(4):370‐2. [MEDLINE: ] - PubMed
Esler 2003 {published and unpublished data}
    1. Esler CN, Blakeway C, Fiddian NJ. The use of a closed‐suction drain in total knee arthroplasty. A prospective, randomised study. Journal of Bone and Joint Surgery. British Volume 2003; Vol. 85‐B, issue 2:215‐7. - PubMed
    1. Esler CN, Fiddian NJ, Natarajan R, Blakeway C. Efficacy of closed suction drainage in primary total knee arthroplasty [abstract]. Journal of Bone and Joint Surgery. British Volume 1996;78 Suppl 1:64.
Gartsman 1997 {published data only}
    1. Gartsman GM, Milne JC, Russell JA. Closed wound drainage in shoulder surgery. Journal of Shoulder and Elbow Surgery 1997;6(3):288‐90. - PubMed
Gonzalez DV 2004 {published data only}
    1. Gonzalez Della Valle A, Slullitel G, Vestri R, Comba F, Buttaro M, Piccaluga F. No need for routine closed suction drainage in elective arthroplasty of the hip. Acta Orthopaedica Scandinavica 2004;75(1):30‐3. - PubMed
Holt 1997 {published data only}
    1. Holt BT, Engh GA, Parks NL. A comparative study of the effects of closed suction drainage vs. no drainage after primary total knee arthroplasty [Abstract]. Orthopaedic Transactions 1995;19(2):333.
    1. Holt BT, Parks NL, Engh GA, Lawrence JM. Comparison of closed‐suction drainage and no drainage after primary total knee arthroplasty. Orthopedics 1997;20(12):1121‐4. - PubMed
Jenny 2001 {published data only}
    1. Boeri C, Jenny JY, Kehr P. Absence of postoperative drainage after knee arthroplasty does not increase the risk of complication: a prospective randomised comparative study [abstract]. Journal of Bone and Joint Surgery. British Volume 2001;83 Suppl 1:65.
    1. Jenny JY, Boeri C, Lafare S. No drainage does not increase complication risk after total knee prosthesis implantation: a prospective, comparative, randomized study. Knee Surgery, Sports Traumatology, Arthroscopy 2001;9(5):299‐301. - PubMed
Johansson 2005 {published data only}
    1. Johansson T, Engquist M, Pettersson L‐G, Lisander B. Blood loss after total hip replacement; a prospective randomized study between wound compression and drainage. Journal of Arthroplasty 2005;20(8):967‐71. - PubMed
Karahan 2005 {published data only}
    1. Karahan M, Erol B, Bekiroglu N, Uyan D. Effect of drain placed in the donor site in the early postoperative period after arthroscopically assisted anterior cruciate ligament reconstruction with quadrupled hamstring tendons. American Journal of Sports Medicine 2005;33(6):900‐6. - PubMed
Kim 1998a {published data only}
    1. Kim YH, Cho SH, Kim RS. Drainage versus nondrainage in simultaneous bilateral total hip arthroplasties. Journal of Arthroplasty 1998;13(2):156‐61. - PubMed
Kim 1998b {published data only}
    1. Kim YH, Cho SH, Kim RS. Drainage versus nondrainage in simultaneous bilateral total knee arthroplasties. Clinical Orthopaedics & Related Research 1998;(347):188‐93. - PubMed
Lang 1998 {published data only}
    1. Bosse MJ, Lang GJ, Richardson M, Gravitte K, Meyer RA, Sims S, et al. Efficacy of surgical wound drainage in orthopaedic trauma patients: a randomized prospective trial [abstract]. Orthopaedic Transactions 1997;21(4):1371. - PubMed
    1. Lang GJ, Richardson M, Bosse MJ, Greene K, Meyer RA, Sims SH, et al. Efficacy of surgical wound drainage in orthopaedic trauma patients: a randomized prospective trial. Journal of Orthopaedic Trauma 1998;12(5):348‐50. - PubMed
    1. Lang GJ, Richardson MW, Bosse MJ, Gravitte KD, Meyer RA, Sims S, et al. Efficacy of surgical wound drainage in orthopaedic trauma patients: a randomized prospective trial [abstract]. Orthopaedic Transactions 1997;21(2):577‐8. - PubMed
Lautenbach 2000 {published data only}
    1. Lautenbach EEG, Tiemessen CH, Cunningham S. How effective is suction drainage?. South African Bone and Joint Surgery 2000;10(3):14‐17.
    1. Tiemessen CH, Lautenbach EEG, Cunningham S, Farah A. How effective is suction drainage? [abstract]. Journal of Bone and Joint Surgery. British Volume 1997;79 Suppl 4:442.
Leb 1995 {published data only}
    1. Leb RB, Parker RD, Cohn BT, Fabian V. The efficacy of closed suction drainage in total knee arthroplasty [abstract]. Orthopaedic Transactions 1995;19(2):332‐3.
Mengal 2001 {published data only}
    1. Mengal B, Aebi J, Rodriguez A, Lemaire R. A prospective randomized study of wound drainage versus non drainage in primary total hip or knee replacement [Abstract]. Journal of Bone and Joint Surgery. British Volume 1999;81 Suppl 2:244‐5.
    1. Mengal B, Aebi J, Rodriguez A, Lemaire R. A prospective randomized study of wound drainage versus non‐drainage in primary total hip or knee arthroplasty [Drainage ou non‐drainage postoperatoire dans les arthroplasties totales primaires de hanche et de genou: etude prospective randomisee]. Revue de Chirurgie Orthopedique et Reparatrice de l Appareil Moteur 2001;87(1):29‐39. - PubMed
Murphy 1993 {published data only}
    1. Murphy JP, Scott JE. The effectiveness of suction drainage in total hip arthroplasty. Journal of the Royal Society of Medicine 1993;86(7):388‐9. - PMC - PubMed
Niskanen 2000 {published data only}
    1. Korkala OL, Niskanen RO, Kuokkanen HOM, Haapala JK, Kaukonen J‐P. Primary total knee replacement: with or without drain? [abstract]. Journal of Bone and Joint Surgery. British Volume 1999;81(Suppl 2):245.
    1. Niskanen RO, Korkala OL, Haapala J, Kuokkanen HO, Kaukonen JP, Salo SA. Drainage is of no use in primary uncomplicated cemented hip and knee arthroplasty for osteoarthritis; a prospective randomized study. Journal of Arthroplasty 2000;15(5):567‐9. - PubMed
Nixon 2000 {published data only}
    1. Nixon J. Wound drainage ‐ the long term results after primary hip and knee arthroplasty [abstract]. Journal of Bone and Joint Surgery. British Volume 2000;82 Suppl 2:125.
Ovadia 1997 {published data only}
    1. Ovadia D, Luger E, Bickels J, Menachem A, Dekel S. Efficacy of closed wound drainage after total joint arthroplasty: A prospective randomized study. Journal of Arthroplasty 1997;12(3):317‐21. - PubMed
Paessler 1997 {published data only}
    1. Brand B, Buchgraber A, Passler HH. Are redon drainages necessary in cruciate ligament operations? [abstract] [Sind redondrainagen bel vorderen kreuzbandersafzoperationen erforderlich?]. Hefte Zur Unfallchirurg 1996;262:207.
    1. Paessler HH, Buchgraber A. Is wound drainage in ACL reconstructive surgery necessary? A prospective and randomized study [abstract]. Orthopaedic Transactions 1997;21(4):1233‐4.
Payne 1996 {published data only}
    1. Payne DH, Fischgrund JS, Herkowitz HN, Barry RL, Kurz LT, Montgomery DM. Efficacy of closed wound suction drainage after single‐level lumbar laminectomy. Journal of Spinal Disorders 1996;9(5):401‐3. - PubMed
Ravikumar 2001 {published data only}
    1. Ravikumar KJ, Alwan T, Fordyce MJF, Tuson KWR. Drainage versus non‐drainage in total hip arthroplasty. A prospective randomised study. Hip International 2001;11(1):49‐54.
Ritter 1994 {published data only}
    1. Ritter MA, Keating EM, Faris PM. Closed wound drainage in total hip or total knee replacement. A prospective, randomized study. Journal of Bone and Joint Surgery. American Volume 1994;76(1):35‐8. - PubMed
Sasso 1998 {published data only}
    1. Sasso RC, Williams JI, Dimasi N, Meyer PR Jr. Postoperative drains at the donor sites of iliac‐crest bone grafts. A prospective, randomized study of morbidity at the donor site in patients who had a traumatic injury of the spine. Journal of Bone and Joint Surgery. American Volume 1998;80(5):631‐5. - PubMed
Straw 2003 {published data only}
    1. Straw R, Colclough K, Geutjens GG. Arthroscopically assisted ACL reconstruction. Is a drain necessary?. Knee 2003;10(3):283‐5. - PubMed
Tjeenk 2005 {published data only}
    1. Tjeenk RM, Peeters MP, Ende E, Kastelein GW, Breslau PJ. Wound drainage versus non‐drainage for proximal femoral fractures. A prospective randomised study. Injury 2005;36(1):100‐4. - PubMed
Varley 1995 {published data only}
    1. Varley GW, Milner S. Wound drains in proximal femoral fracture surgery. Report of a randomised prospective trial of 177 patients [abstract]. Journal of Bone and Joint Surgery. British Volume 1994;76 Suppl 2 & 3:147‐8.
    1. Varley GW, Milner S, Turner GM, Crisp AJ, Szypryt EP. Ultrasound assessment of the efficacy of wound drains. Journal of the Royal College of Surgeons of Edinburgh 1994;39(2):97‐9. - PubMed
    1. Varley GW, Milner SA. An objective assessment of wound drains in hip fractures [abstract]. Journal of Bone and Joint Surgery. British Volume 1993;75(Suppl 2):110.
    1. Varley GW, Milner SA. Wound drains in proximal femoral fracture surgery: A randomized prospective trial of 177 patients. Journal of the Royal College of Surgeons of Edinburgh 1995;40(6):416‐8. - PubMed
    1. Varley GW, Milner SA. Wound drains in proximal femoral fracture surgery: A randomized prospective trial of 177 patients. Journal of the Royal Society of Medicine 1995;88:42P‐44P. - PMC - PubMed
Walmsley 2005 {published data only}
    1. Hill RMF, Brenkel I. Drain vs no drain in unilateral total hip arthroplasty: a randomised prospective trial. Journal of Bone and Joint Surgery. British Volume 2003;85‐B(Supp II):104. - PubMed
    1. Walmsley PJ, Kelly MB, Hill RMF, Brenkel I. A prospective, randomised, controlled trial of the use of drains in total hip arthroplasty. Journal of Bone and Joint Surgery. British Volume 2005;87‐B(10):1397‐401. - PubMed
Widman 2002 {published data only}
    1. Widman J, Jacobsson H, Larsson SA, Isacson J. No effect of drains on the postoperative hematoma volume in hip replacement surgery: a randomized study using scintigraphy. Acta Orthopaedica Scandinavica 2002;73(6):625‐9. - PubMed

References to studies excluded from this review

Ashraf 2001 {published data only}
    1. Ashraf T, Darmanis S, Krikler SJ. Effectiveness of suction drainage after primary or revision total hip and total knee arthroplasty. Orthopedics 2001;24(12):1158‐60. - PubMed
Beer 1991 {published data only}
    1. Beer KJ, Lombardi AV Jr, Mallory TH, Vaughn BK. The efficacy of suction drains after routine total joint arthroplasty [erratum appears in Journal of Bone and Joint Surgery. American Volume 1991;73(5):791]. Journal of Bone and Joint Surgery. American Volume 1991;73(4):584‐7. - PubMed
Berman 1990 {published data only}
    1. Berman AT, Fabiano D, Bosacco SJ, Weiss AA. Comparison between intermittent (spring‐loaded) and continuous closed suction drainage of orthopedic wounds: a controlled clinical trial. Orthopedics 1990;13(3):309‐14. - PubMed
Bryan 1969 {published data only}
    1. Bryan RS, Dickson JH, Taylor WF. Recovery of the knee following meniscectomy. Journal of Bone and Joint Surgery. American Volume 1969;51(5):973‐8. - PubMed
Gehrig 2005 {published data only}
    1. Gehrig LM, Sadasivan KK, Marino AA, Albright JA. External suction drainage in primary total joint arthroplasties. American Journal of Orthopedics 2005;34(4):164‐6. - PubMed
Gerngross 1992 {published data only}
    1. Gerngross H, Marquardt KJ. What suction drainage is optimal for drainage of wound secretion? A clinico‐experimental study exemplified by the knee joint [Welcher Sog ist fur die Ableitung von Wundsekret der optimale? Eine klinisch‐experimentelle Studie am Beispiel des Kniegelenks]. Chirurg 1992;63(5):447‐53. - PubMed
Graupe 1996 {published data only}
    1. Graupe F, Eyssel M, Stock W. Slit drainage in hip endoprosthesis ‐ also an alternative in trauma surgery? A prospective follow‐up study [Die Slitdrainage in der Huftendoprothetik ‐ Eine alternative auch in der unfallchirurgie? Eine prospektive beobachtungsstudie]. Unfallchirurgie 1966;22(5):223‐7. - PubMed
Kohler 2000 {published data only}
    1. Kohler S, Awiszus F, Neumann W, Ratayski H. Gravital drainage is best suited as care after total hip end prosthetic operations. Results of a prospective randomised controlled study [abstract] [Die schwerkraftdrainage ist fur die versorgung nach hufttotalendoprothesenoperationen am besten geeignet. Ergebnisse einer prospektiven randomisierten kontrollierten studie]. Hefte zur der Unfallchirurg 2000;275:415‐6.
Labek 1998 {published data only}
    1. Labek G, Boehler N. The influence of Redon drainages on blood loss and early outcome in total hip arthoplasty [abstract]. Journal of Bone and Joint Surgery. British Volume 1999;81(Suppl 2):244.
    1. Labek G, Bohler N. Blood transfusion in total hip endoprosthesis operations in relation to Redon drainage and pressure bandages. An innovation in surgical method [Blutverbrauch bei Hufttotalendoprothesenoperationsen in abhangigkeit von redondrainage und druckverband: eine innovation im operativen vorgehnen]. Zeitschrift fur Orthopadie und Ihre Grenzgebiete 1998;136(5):433‐8. [MEDLINE: ] - PubMed
    1. Labek G, Bohler N. Packed red cell requirement after total hip replacement depending on recon drainage and compression bandage [Blutverbrauch bei hufttotalendoprothesenoperationen in abhangigheit von redondrainage und druckverband]. European Journal of Trauma 2001;(Suppl 1):175‐6.
Mac 1991 {published data only}
    1. Mac HL, Reynolds MA, Treston‐Aurand J, Henke JA. Comparison of autoreinfusion and standard drainage systems in total joint arthroplasty patients. Orthopaedic Nursing 1993;12(3):19‐25. - PubMed
Mah 1996 {published data only}
    1. Mah ET, Wrobel J. Effects of different wound drainage systems on blood loss following total knee and hip arthroplasties. J Orthopaedic Surgery 1996;4(1):83‐88.
Martin 2004 {published data only}
    1. Martin A, Prenn M, Spiegel T, Sukopp C, Strempel A. Relevance of wound drainage in total knee arthropalasty; a prospective comparative study [German] [Die bedeutung der wunddrainage in der knieendoprothetik ‐ eine prospektive vergleichsstudie]. Zeitschrift fur Orthopadie und Ihre Grenzgebiete 2004;142(1):46‐50. - PubMed
Nicolajsen 1996 {published data only}
    1. Nicolajsen K, Kramhoft M, Hansen D. The use of closed suction drains in femoral neck and intertrochanteric fractures [abstract]. Acta Orthopaedica Scandinavica. Supplementum 1996;267:30.
Padala 2003 {published data only}
    1. Padala PR, Rouholamin E. Are tourniquets and drains really required in primary total knee replacements? A prospective study using adrenaline and saline infiltration as an alternative method to tourniquet. Haema 2003;6(4):529‐31.
    1. Padala PR, Rouholamin E, Mehta RL. The role of drains and tourniquets in primary total knee replacement. A comparative study of TKR performed with drains and tourniquet versus no drains and adrenaline and saline infiltration. Journal of Knee Surgery 2004;17(1):24‐7. - PubMed
Pomeroy 1995 {unpublished data only}
    1. Pomeroy DL, Campbell MJ, Empson JA, Stovall D, Davis J. [Evaluation of postoperative suction drainage in primary total knee arthroplasty [Abstract]]. American Academy of Orthopaedic Surgeons Annual Meeting; 1995 Feb 16‐21; Orlando (FL). 1995:http://www.aaos.org/wordhtml/anmeet95/sciprog/171.htm (accessed 14/07/01).
Reilly 1986 {published data only}
    1. Reilly TJ, Gradisar IA, Jr, Pakan W, Reilly M. The use of postoperative suction drainage in total knee arthroplasty. Clinical Orthopaedics and Related Research 1986;280:238‐42. - PubMed
Sen 2005 {published data only}
    1. Sen O, Kizilkilic O, Aydin MV, Yalcin O, Erdogan B, Cekinmez M, et al. The role of closed‐suction drainage in preventing epidural fibrosis and its correlation with a new grading system of epidural fibrosis on the basis of MRI. European Spine Journal 2005;14(4):409‐14. - PMC - PubMed
Seyfert 2002 {published data only}
    1. Seyfert C, Schulz K, Pap G. The influence of the drain suction in knee arthroplasty [Einfluss des Drainagesoges auf den postoperativen Verlauf nach Knieendoprothesen‐Implantation]. Zentralblatt fur Chirurgie 2002;127(10):886‐9. - PubMed
Tatari 2005 {published data only}
    1. Tatari H, Dervisby M, Muratli K, Ergor A. Report of experience in 190 patients with the use of closed suction drainage in arthropscopic knee procedures. Knee Surgery Sports Traumatology Arthroscopy 2005;13(6):458‐62. - PubMed
Trammell 1991 {published data only}
    1. Trammell TR, Fisher D, Brueckmann FR, Haines N. Closed‐wound drainage systems. The Solcotrans Plus versus the Stryker‐CBC ConstaVAC. Orthopaedic Review 1991;20(6):536‐42. - PubMed
Tsumara 2006 {published data only}
    1. Tsumara N, Yoshiya S, Chin T, Shiba R, Kohso K, Doita M. A prospective comparison of clamping the drain or post‐operative salvage of blood in reducing blood loss after total knee arthroplasty. Journal of Bone and Joint Surgery. British Volume 2006;88‐B(1):49‐53. - PubMed
Willemen 1991 {published data only}
    1. Willemen D, Paul J, White SH, Crook DW. Closed suction drainage following knee arthroplasty. Effectiveness and risks. Clinical Orthopaedics and Related Research 1991;264:232‐4. - PubMed
Zamora‐Navas 1999 {published data only}
    1. Zamora‐Narvas P, Collado‐Torres F, Torre‐Solis F. Closed suction drainage after knee arthroplasty. A prospective study of the effectiveness of the operation and of bacterial contamination. Acta Orthopaedica Belgica 1999;65(1):44‐7. - PubMed

References to studies awaiting assessment

Hill 2000 {published data only}
    1. Hill RMF, Brenkel I. Drain vs no drain in unilateral and bilateral knee arthroplasty: a randomised prospective trial [abstract]. Journal of Bone and Joint Surgery. British Volume 1999;82 Suppl 1:http://www.jbjs.org.uk/proceedings.htm (accessed 21/08/2003).
    1. Hill RMF, Brenkel I. Drain vs no drain in unilateral and bilateral knee arthroplasty: a randomised prospective trial [abstract]. Journal of Bone and Joint Surgery. British Volume 2000;82 Suppl 1:68.

Additional references

Higgins 2003
    1. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta‐analyses. BMJ 2003;327:556‐60. - PMC - PubMed
Higgins 2005
    1. Higgins JPT, Green S, editors. Highly sensitive search strategies for identifying reports of randomized controlled trials in MEDLINE. Cochrane Handbook for Systematic Reviews of Interventions 4.2.5 [updated May 2005]; Appendix 5b. www.cochrane.org/resources/handbook/hbook.htm (accessed 31 May 2005).
Madhok 2006
    1. Madhok R, Shaw LJ, Gillespie LD. Bone, Joint and Muscle Trauma Group. About the Cochrane Collaboration. In: The Cochrane Library, Issue 1, 2006. Chichester: Wiley. Updated quarterly.
Willett 1988
    1. Willett KM, Simmons CD, Bentley G. The effects of suction drains after total hip replacement. Journal of Bone and Joint Surgery. British Volume 1988;70(4):607‐10. - PubMed

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