Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Sep 3;97(5):700-4.
doi: 10.1038/sj.bjc.6603893. Epub 2007 Jul 17.

Smoking, alcohol and gastric cancer risk in Korean men: the National Health Insurance Corporation Study

N Y Sung  1 , K S Choi, E C Park, K Park, S Y Lee, A K Lee, I J Choi, K W Jung, Y J Won, H R Shin
Affiliations

Smoking, alcohol and gastric cancer risk in Korean men: the National Health Insurance Corporation Study

N Y Sung et al. Br J Cancer. .

Abstract

We investigated the risk of gastric cancer by subsite in relation to cigarette smoking and alcohol in a large population-based cohort of 669 570 Korean men in an insurance plan followed for an average 6.5 years, yielding 3452 new cases of gastric cancer, of which 127 were cardia and upper-third gastric cancer, 2409 were distal gastric cancer and 1007 were unclassified. A moderate association was found between smoking, cardia and upper-third (adjusted relative risk (aRR) 2.2; 95% confidence interval (CI) 1.4-3.5) and distal cancers (aRR=1.4; 95% CI=1.3-1.6). We also found a positive association between alcohol consumption and distal (aRR=1.3; 95% CI=1.2-1.5) and total (aRR=1.2; 95% CI=1.1-1.4) gastric cancer. Combined exposure to high levels of tobacco and alcohol increased the risk estimates further; cardia and upper-third gastric cancers were more strongly related to smoking status than distal gastric cancer.British Journal of Cancer (2007) 97, 700-704. doi:10.1038/sj.bjc.6603893 www.bjcancer.com Published online 17 July 2007.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Brenner H, Arndt V, Bode G, Stegmaier C, Ziegler H, Stumer T (2002) Risk of gastric cancer among smokers infected with Helicobacter pylori. Int J Cancer 98: 446–449 - PubMed
    1. Gammon MD, Schoenberg JB, Ahsan H, Risch HA, Vaughan TL, Chow WH, Rotterdam H, West AB, Dubrow R, Stanford JL, Mayne ST, Farrow DC, Niwa S, Blot WJ, Fraumeni JF (1997) Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia. J Natl Cancer Inst 89: 1277–1284 - PubMed
    1. Inoue M, Tajima K, Hirose K, Kuroishi T, Gao CM, Kitoh T (1994) Life-style and subsite of gastric cancer – joint effect of smoking and drinking habits. Int J Cancer 56: 494–499 - PubMed
    1. International Agency for Research on Cancer (1994) IARC monograph on the evaluation of the carcinogenic risks to humans, Schistosomes, liver flukes and Helicobacter pylori, vol. 61. Lyon, France: International Agency for Research on Cancer - PMC - PubMed
    1. International Agency for Research on Cancer (2004) Tobacco smoke and involuntary smoking. In IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, vol. 83, pp 557–613, Lyon, France: International Agency for Research on Cancer - PMC - PubMed

Publication types