doi: 10.1038/nchembio0807-442.
Scaffold composition and biological relevance of screening libraries
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- PMID: 17637770
- DOI: 10.1038/nchembio0807-442
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Scaffold composition and biological relevance of screening libraries
Nat Chem Biol.
2007 Aug.
Abstract
The chemical scaffolds from which screening libraries are built have strong influence on the libraries' utility for screening campaigns. Here we present analysis of the scaffold composition of several types of commercially available screening collections and compare those compositions to those of drugs and drug candidates.
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