doi: 10.1093/jnci/56.3.671.
Malignant transformation of hamster brain cells in vitro by human papovavirus Bk
- PMID: 176404
- DOI: 10.1093/jnci/56.3.671
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Malignant transformation of hamster brain cells in vitro by human papovavirus Bk
J Natl Cancer Inst.
1976 Mar.
Abstract
Human papovavirus BK caused the malignant transformation in vitro of brain cells prepared from newborn hamsters. The transformed cells produced BK virus T antigen and grew as tumors after sc inoculation ito hamsters that developed antibodies to BK virus T antigen. The histopathology of the tumors revealed an undifferentiated glioma.
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