Comment
doi: 10.1073/pnas.0705319104.
Epub 2007 Jul 18.
Quaternary structure of p53: the light at the end of the tunnel
Affiliations
- PMID: 17640907
- PMCID: PMC1941454
- DOI: 10.1073/pnas.0705319104
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Comment
Quaternary structure of p53: the light at the end of the tunnel
Proc Natl Acad Sci U S A.
.
No abstract available
Conflict of interest statement
The author declares no conflict of interest.
Figures
Cartoon models of p53 bound to DNA. (A) A model based on the structural model proposed by Kitayner et al. (13). (B) A model based on the EM structure proposed by Tidow et al. (11). The CD tetramer is composed of two identical dimers shown as pairs of green and cyan balloons. The Tet is shown as four elongated rectangles, each representing a long α-helix and a short β-strand. The two tetramers are connected by unstructured chains shown as broken lines of the corresponding color codes. The unstructured N and C termini are shown as curved arrows. The DNA response element is represented by a blue cylinder.
Comment on
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Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex.Proc Natl Acad Sci U S A. 2007 Jul 24;104(30):12324-9. doi: 10.1073/pnas.0705069104. Epub 2007 Jul 9. Proc Natl Acad Sci U S A. 2007. PMID: 17620598 Free PMC article.
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