Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Apr;56(4):843-9.
doi: 10.1093/jnci/56.4.843.

Epithelial cell cultures from normal and cancerous human tissues

R B Owens, H S Smith, W A Nelson-Rees, E L Springer

Epithelial cell cultures from normal and cancerous human tissues

R B Owens et al. J Natl Cancer Inst. 1976 Apr.

Abstract

Thirty epithelial cell strains were isolated from human carcinomas and normal epithelial tissues by collagenase digestion and selective removal of fibroblasts with trypsin-Versene. Most strains were obtained from metastatic carcinomas or epithelia of the urinary and intestinal tracts. The success rate for growth of both neoplastic and normal tissues (excluding skin) was 38%. Six of these strains showed gross morphologic and chromosome changes typical of malignant cells. Nine resembled normal epithelium. The other 15 exhibited some degree of morphologic change from normal.

PubMed Disclaimer

Publication types

LinkOut - more resources